Disease: Mammary Tumorigenesis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
MELK Q14680 maternal embryonic leucine zipper kinase Kinase 4.5E-22 0.566 0.577
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
KAT5 Q92993 lysine acetyltransferase 5 8.8E-02 0.534 0.769
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
HMGA2 P52926 high mobility group AT-hook 2 Nucleic acid binding 0.87 0.429 0.808
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923